Enzymatic Basis for Active Transport of Na+ and K+ across Cell Membrane.

Afhnity for Monovalent Cations. ............................................. 597 Relationship of Enzyme System to ATP. ...................................... 598 Isolation of Enzyme System from Other Cells with Active Transport of Na+ and K+ ................................................................. 602 Location of Enzyme System in the Cell. ...................................... 604 Effect of Cardiac Glycosides. ................................................ 605 Quantitative Relation between Effect of Na+ + K+ on Enzyme System and Active Transport in Intact Cell. .......................................... 606 Nature of Enzyme System. .................................................. 607 Relation of (Na + + K+)-Activated Enzyme System to Active Transport of Cations. ................................................................ 6 10 Conclusion. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6’4